Reactivity in Chemistry

Mechanisms of the Tricarboxylic Acid Cycle

TC4.  Solutions for Selected Problems

Problem TC1.1.

Steps 3 and 4 (isocitrate to alpha-ketoglutarate and alpha-ketoglutarate to succinyl coenzyme A).


Problem TC1.2.

Step 5 (succinyl coenzyme A to succinate).


Problem TC1.3.

Steps 3 (isocitrate to alpha-ketoglutarate; NADH), 4 (alpha-ketoglutarate to succinyl coenzyme A; NADH), 6 (succinate to malate; FADH2), and 8 (malate to oxaloacetate; NADH).  

Problem TC2.1.



Problem TC2.2.



Problem TC2.3.



Problem TC2.4.



Problem TC2.5.



Problem TC3.1.


Problem TC3.2.


Problem TC3.3.


Problem TC3.4.

The anion that results from deprotonation of tyrosine is resonance-stabilised, but the anion that results from deprotonation of serine is not.  The tyrosine anion is more stable compared to the serine anion and therefore the tyrosine anion forms more readily.


Problem TC3.5.


Problem TC3.6.


Problem TC3.7.


Problem TC3.8.


This site is written and maintained by Chris P. Schaller, Ph.D., College of Saint Benedict / Saint John's University (with contributions from other authors as noted).  It is freely available for educational use.

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This material is based upon work supported by the National Science Foundation under Grant No. 1043566.

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