Thermodynamics of the GTP-GDP-operated Conformational Switch of Selenocysteine-specific Translation Factor SelB. Alena Paleskava, Andrey L. Konevega and Marina V. Rodnina . The Journal of Biological Chemistry, 287, 27906-27912 (2012).  doi: 10.1074/jbc.M112.366120  .

Summary

5.  The binding interactions between SelB and GTP are enthalpically favored and entropically disfavored and proceed with a negative - DCp. 

a.  List possible factors (not including buffer solution DHion) that could lead to enthalpy changes on binding

b.  List possible factors (not including buffer solution DHion that could lead to enthalpy changes on binding

c.  List possible factors that could lead to heat capacity changes on binding

 

Answers

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