Lactose Permease complexed with thiodigalactoside

Lactose Permease is produced by the lac Y gene, and transports the ß-galactoside into E. coli. This protein has 12 α-helices which span the cell membrane. The ligand, thiodigalactoside (TDG), is an analog of lactose, and is shown in spacefill in the selections below.  

Wire Frameee

Backbone

Backbone and sidechains

Cartoon showing hydrogen bonds

Cartoon and Wireframe

 

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