Supporting reading list of chapters from Garrett and Grisham

BACKGROUND MATERIAL:   Please read the following material on your own. It will not be covered directly in class, but you will be required to know the material.

• Chapt 1 - Chemistry is the Logic of Biological Phenomena
• Chapt 32 - The Genetic Code; 1069-1074. [Given a DNA coding sequence, you must be able to determine the corresponding protein sequence.

LIPIDS AND MEMBRANES

• Chapt 8 - Lipids
• Chapt 9 - Membranes (to page 270).

PROTEIN STRUCTURE

• Chapt 4 - Amino Acids
• Chapt 5 - Proteins: Biological Function and Primary Structure (Appendix covered in lab)
• Chapt 6 - Proteins: Secondary, Tertiary, and Quaternary Structure
• Chapt 9 - Membranes: 9.2 - Structure of Membrane Proteins

CARBOHYDRATES

• Chapt 7 - Carbohydrates
• Chapt 9 - Membranes: 9.3 - Membrane and Cell-Surface Polysaccharides; 9.4 - Glycoproteins

NUCLEIC ACID STRUCTURE (covered in lab)

• Chapt 11 - Nucleotides and Nucleic Acids
• Chapt 12 - Structure of Nucleic Acids
• Chapt 8 - Recombinant DNA

BINDING

• Chapt 15 - Enzyme Specificity and Allosteric Regulation, 460-462;
• Chapt 15 Special Focus - Hemoglobin and Myoglobin, 480-493.
• Chapt 15: Allosteric Enzymes, 469-480

TRANSPORT

• Chapt 10 - Membrane Transport, 296-300.

KINETICS

• Chapt 14 - Enzyme Kinetics
• Chapt 15 - Enzyme Specificity and Allosteric Regulation

CATALYSIS

• Chapt 16 - Mechanisms of Enzyme Action
• Chapt 18 - Metabolism: An Overview; special emphasis on coenzymes and vitamins
• Supplement - Enzyme catalyzed reactions in organic solvents

ENERGY TRANSDUCTION

• Supplement - The Chemistry of Dioxygen
• Biological Oxidation Reactions - Dehydrogenases, Mono and Dioxygenases, and Oxidases;
• Chapt 18 - Metabolism: An Overview
• Chapt 3 - 3.6-3.7: High Energy Biomolecules, 66-79
• ATP and Oxidative Phosphorylation Reactions in Glycolysis - pg 622-630;
• Chapt 21 - Electron Transport and Oxidative Phosphorylation
• Chapt 22 - Photosynthesis; pg 709-730

SIGNAL TRANSDUCTION

• Chapter 10: (Membrane Transport) Energy Transduction - Uses of ATP - Active Transport 300-325
• Supplement: Excitable Membranes, Neurotransmission, and Sensory Systems -Signal Transduction: Nerve Cells - Neural Chemistry; S41-63
• Chapter 34: Signal Transduction at Cell Membranes - Protein Kinases/Phosphatases S1-S40