Structure & Reactivity
Nuclear Magnetic Resonance Spectroscopy
NMR2D6. 2D NMR Practice
All problems are contributions from Edward McIntee and Kate Graham, College of Saint Benedict | Saint John's University
The following problems involve real samples. Note that you may need to check for peaks due to solvent. Helpful tables may be found here.
Problem NMR2D6.1.*
Present an analysis of the following data and propose a structure.
MW: 86 amu.
The full 1H NMR spectrum in CDCl3:
Note that the m beside one of the integral values stands for milli (one thousandth). 61.29m = 0.06129 units.
An expansion of the 1H NMR spectrum:
Another expansion:
A 13C NMR spectrum:
COSY spectrum:
HMQC spectrum:
HMBC spectrum:
Problem NMR2D6.2.*
Present an analysis of the following data and propose a structure.
MW: 202 amu
The full 1H NMR spectrum in D2O:
An expansion:
13C NMR:
COSY:
Problem NMR2D6.3.*
Present an analysis of the following data and propose a structure.
MW: 164 amu
The full 1H NMR spectrum in CDCl3:
An expansion of the 1H NMR spectrum:
Another expansion:
13C NMR spectrum:
COSY spectrum:
HMQC:
HMBC:
Problem NMR2D6.4.*
Present an analysis of the following data and propose a structure.
MW: 131 amu
The full 1H NMR spectrum in D2O:
An expansion:
13C NMR:
COSY:
HMBC:
Problem NMR2D6.5.*
Present an analysis of the following data and propose a structure.
MW: 144 amu
The 1H NMR spectrum in CDCl3:
An expansion of the 1H NMR spectrum:
13C NMR spectrum:
COSY:
An expansion of the COSY spectrum:
HMBC:
An expansion of the HMBC spectrum:
Problem NMR2D6.6.*
Present an analysis of the following data and propose a structure.
MW: 164 amu
The full 1H NMR spectrum in CDCl3:
AN expansion:
13C NMR:
COSY:
Expansion of COSY spectrum:
Problem NMR2D6.7.*
Present an analysis of the following data and propose a structure.
MW: 129 amu
The full 1H NMR spectrum in D2O:
13C NMR spectrum:
COSY spectrum:
Problem NMR2D6.8.*
Present an analysis of the following data and propose a structure.
MW: 173 amu
The full 1H NMR spectrum in CDCl3:
An expansion of the 1H NMR spectrum:
13C NMR spectrum:
COSY:
HMQC:
HMBC:
Problem NMR2D6.9.*
Present an analysis of the following data and propose a structure.
MW: 145 amu
The full 1H NMR spectrum in D2O:
An expanded view of 1H NMR spectrum:
Another expanded view:
13C NMR spectrum:
COSY spectrum:
Problem NMR2D6.10.*
Present an analysis of the following data and propose a structure.
MW: 251 amu
The full 1H NMR spectrum in DMSO-d6:
An expanded view of the 1H NMR spectrum:
Another expansion:
13C NMR spectrum:
COSY spectrum:
Expansion of COSY:
HMQC spectrum:
Problem NMR2D6.11.*
Present an analysis of the following data and propose a structure.
MW: 244 amu
The full 1H NMR spectrum in DMSO-d6:
An expanded view of the 1H NMR spectrum:
Another expansion of the 1H NMR spectrum:
Another expansion of the 1H NMR spectrum:
13C NMR spectrum:
COSY:
An expanded view of the COSY spectrum:
Problem NMR2D6.12.*
Present an analysis of the following data and propose a structure.
MW: 242 amu
The full 1H NMR spectrum in DMSO-d6:
Expansion of the 1H NMR spectrum:
Another expansion:
13C NMR spectrum:
COSY:
An expansion of the COSY spectrum:
Problem NMR2D6.13.*
Present an analysis of the following data and propose a structure.
MW: 152 amu
The full 1H NMR spectrum in CDCl3:
An expansion of the 1H NMR spectrum:
13C NMR spectrum in CDCl3:
COSY spectrum:
HMQC spectrum:
HMBC spectrum:
Problem NMR2D6.14.*
Present an analysis of the following data and propose a structure.
MW: 152 amu
The full 1H NMR spectrum in CDCl3:
13C NMR spectrum:
COSY spectrum:
HMQC spectrum:
HMBC spectrum:
Problem NMR2D6.15.*
Present an analysis of the following data and propose a structure.
MW: 152 amu
The full 1H NMR spectrum in CDCl3:
An expansion of the 1H NMR spectrum:
13C NMR spectrum (the solvent peak is coincident with a sample peak):
COSY spectrum:
HMQC spectrum:
HMBC spectrum (partial; some correlations failed to show up in this experiment):
NMR spectra obtained on a JEOL 400 MHz NMR spectrometer.
All problems are contributions from Edward McIntee and Kate Graham, College of Saint Benedict | Saint John's University
This site was written by Chris P. Schaller, Ph.D., College of Saint Benedict / Saint John's University (retired) with other authors as noted on individual pages. It is freely available for educational use.
Structure & Reactivity in Organic, Biological and Inorganic Chemistry by Chris Schaller is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License.
Send corrections to cschaller@csbsju.edu
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Useful Charts for NMR identification.