Calmodulin EF Hand
Helix - Loop - Helix
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Here is the structure of amino
acids 118-148 of human calmodulin. This proteins binds calcium and
modulates many intracelluar processes - it is a calcium
modulatory protein (or calmodulin). Shown is a
helix-loop-helix supersecondary structure motiff.
Calcium (shown
in spacefill rendering) is bound
in the loop and is coordinated to Glu side chains protruding in from
the loop
Wire Frame
Backbone
Backbone and side
chains
Ca2+ and
side chain interactions
- notice the carboxyl Os interacting with the calcium
Cartoon showing hydrogen bonds
Cartoon and Wireframe
Dot surface and Wireframe
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