METABOLISM IN VARIOUS ORGANS OF VERTEBRATES

ORGAN

FUEL STORE

FUEL EXPORTED

NORMAL FUEL

FUEL IN STARVATION

BRAIN

none

none

glucose

ketone bodies (AcAc)

MUSCLE
SKELETAL
1

glycogen

-lactate during activity
-amino acids during starvation

-fatty acids under rest (aerobic)
- glucose when active (anerobic)

ketone bodies

MUSCLE
CARDIAC
2

negligible

none

fatty acids
glucose

ketone bodies

ADIPOSE TISSUE

TAG's

fatty acids and glycerol

fatty acids

  .

LIVER

glycogen and TAG's

-TAG's in VLDL
-glucose
-ketone bodies

amino acids
-glucose
-fatty acids

amino acids

1,2Skeletal and cardiac muscle differ significantly in function and fuel use. Skeletal muscles varies enormously in fuel needs based on activity and uses both aerobic and anerobic pathways. In contrast the heart activity is more constant, and it is completely aerobic. Also it has no energy reserves.