Characteristics of Antibody-Hen Egg Lysozyme (HEL) Complexes
Antibody | H26-HEL | H63-HEL | H10-HEL | H8-HEL |
Kd (nM) | 7.14 | 3.60 | 0.313 | 0.200 |
Intermolecular Interactions | ||||
H bonds | 24 | 25 | 20 | 23 |
VDW contacts | 159 | 144 | 134 | 153 |
salt bridges | 1 | 1 | 1 | 1 |
Buried Surface Area |
||||
ΔASURF (A2) | 1,812 | 1,825 | 1,824 | 1,872 |
ΔASURF-polar (A2) | 1,149 | 1,101 | 1,075 | 1,052 |
ΔASURF-apolar (A2) | 663 | 724 | 749 | 820 |
Li,Y. et al. Nature: Structural Biology. 6, pg 484 (2003)