Average Changes for 8 Asn to Ala, Leu to Ala, and Ile to Val Mutants
| mutation | ΔVol side chain (A) | % buried | ΔΔG (kcal/mol) (destabilized) |
ΔΔG (cal/mol/A) (destabilized) |
| Asn to Ala | 37.4 | 95 | 2.9 | 78 |
| Leu to Ala | 74.5 | 99 | 3.6 | 48 |
| Ile to Val | 25.8 | 100 | 1.3 | 50 |