Chymotrypsin complexed with
D-LEUCYL-L-PHENYLALANYL-P-FLUOROBENZYLAMIDE (FBA)
Java version
HTML 5 version (does not require Java; downloads and moves
slowly)
For more information see
Biochemistry Online: Chapter 7B - Mechanisms of Enzyme Catalysis
II. General Structure
Wireframe
Cartoon
Cartoon structure with
Inhibitor (Spacefill): FBA;
Red is DLeu-L-Phe,
Green is Fluorobenzylamine
Ser - His - Asp active site
(tube)
Note the location of the Ser OH proximal to the amide
bound in the inhibitor
Disulfide Bridges