Cytochrome C Oxidase

Cytochrome C Oxidase - energy transducer, electron carrier.

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For more information see Biochemistry Online: Chapter 8B - B: BIOLOGICAL OXIDATION REACTIONS DEHYDROGENASES, MONO- AND DIOXYGENASES, AND OXIDASES

II. General Structure

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If you manually rotate the structure, return it to the original orientation before the next selection. The original.

Colored chains

Note the dimeric structure of the enzyme - the large number of colors resulting is from the 26 discrete chains in Cyt. C Oxidase (13 in each dimer).

Backbone
Protein backbone with spacefilling heme (CPK), Cu²⁺ (gold), and Mg²⁺, green
Protein backbone with cytochrome C binding sites and heme/metal groups

Asp and Glu residues in the cytochrome C binding sites green and the heme/metal groups cyan. The negatively charged Asp and Glu residues which comprise the cytochrome C concave binding sites facilitate the binding of cytochrome C, which with a pI of 10.6 has a large positive charge. Observe the close proximity of the binding sites to the heme/metal centers.

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