Triose Phosphate
Isomerase
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I. Introduction
This protein contains both alpha helices and beta sheets. There
are two main classes of these proteins. In one class, represented
by this enzyme, the parallel beta strands form a closed beta
barallel, made up of 8 twisted beta strands. Connecting the beta
strands are alpha helices, so the protein contains an baba..repeat.
The alpha helices are on the outside of the barallel. This specfic
motiff that is found in many proteins is often called the TIM
barallel after this particular protein. The active site of these
proteins at the top of the barallel where loops that connect the
C-terminal ends of the beta strands connect the adjacent alpha
helix.
For more information see
Biochemistry Online: Chapter 2C - Understanding Protein
Conformation
II. General Structure
Wireframe
Backbone
Backbone and Side Chains
Cartoons, H bonds, and Wireframe
Dot Surface and Side Chains