Gs-alpha/adenylate cyclase complex

Java version

HTML 5 version (does not require Java; downloads and moves slowly)

---

I. Introduction

For more information see Biochemistry Online: Chapter 9B - Signal Transduction - Neurochemistry

---

II. General Structure

Wire Frame
Gs-alpha Subunit
Adenylate Cyclase Hetero Dimer
Distinguish Complex Chains by Color (cyclase chain A, cyclase chain B, Gs-alpha chain)
Backbone
Backbone and sidechains
Cartoon showing hydrogen bonds (cyclase chain A, cyclase chain B, Gs-alpha chain)
Forskolin - an agonist (activator) or adenylate cylase
Show GSP (5'-Guanosine-Diphosphate-Monothiophosphate) a non-hydrolyzable analog of GTP which interacts with Gs-alpha
Show all Ligands - GSP (Orange), FOK (yellow)