Rieske Center of Complex III:
Coenzyme C/Cytochrome C Reductase

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I. Introduction

CoThe Rieske center of Complex III is an iron/sulfur cluster with formula Fe2S2.  In contrast to other FeS cluster, one Fe is also coordinated to 2 His side chains while the other is coordinated to2 2 Cys side chains. 

For more information see Biochemistry Online: Chapter 8C-6 - Complex III

II. General Structure

The His and Cys amino acids that coordinate to the Fes in the Rieske cluster are shown below in stick form. Sulfide (S2-) is shown in yellow.

Rieske Center of Complex III with coordinating His and Cys side chains