Biochemistry Online: An Approach Based on Chemical Logic

Biochemistry Online

CHAPTER 1 - LIPID STRUCTURE

C: Dynamics of Membrane Lipids

BIOCHEMISTRY - DR. JAKUBOWSKI

02/12/2016

Learning Goals/Objectives for Chapter 1C:  After class and this reading, students will be able to

  • state the different kinds of dynamical motions of double chain amphiphiles in lipid bilayers, differentiating between motion of entire molecules and motion within a molecule
  • describe experiments that could be used to study lateral and flip-flop diffusion in vitro and in vivo
  • explain the use of exogenous labels (fluorescent, radioactive, electron spin resonance) that allow laboratory determination of lipid location and movement
  • explain similarities and differences in measurement and explanations of phase transitions in water and in lipid vesicle
  • explain the biological effects and necessities of membrane dynamics

Sections

1C1 Dynamics of Membranes


1C2 Lipid Distribution in Cells


1C3 Lipid Rafts


1C4 Lipid Conformational Transitions


1C5 Membrane Permeability


1C6 General Links and References

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Archived version of full Chapter 1C:  Dynamics of Membrane Lipids