Learning Goals/Objectives for Chapter 2G:  After class and this reading, students will be able to:

• find web based proteomics protein to analyze protein sequences and structures
• describe the basis for methods used to predict the secondary structure and hydrophobic structures of proteins
• analyze secondary structure and hydropathy plots from web-based proteomics programs.
• describe differences between integral and peripheral membranes proteins, and how each could be purified.
• explain how hydropathy and secondary structure plots can be used to predict membrane spanning sequences of proteins
• describe in general the theoretical and empirically based methods to predict protein tertiary structure from a primary sequence
• describe possible early intermediates in protein folding as determined by theoretical methods