SPRING 2009 BCHM 321 CLASS SCHEDULE

Day	Date	Chapter	Assignment PS Moodle Qz Pre-Class Questions:
1	1/13 T A2	syllabus Interactive Web Programs Worried results; Survey Results Chemical Logic; simple molecules make complex polymers	SAMPLE QUIZ Pre-class Student Survey Pre-Class Questions: Are you worried?
2	1/15 R A4	Chapt 1A - Lipid Struct. Chapt 1B - Lip in Water	Pre-Class Questions Lipid Structure: A. Lipid Structure - Question Pre-Class Questions: Lipid Structure: B. Lipids in Water - Question
3	1/19 M A6	Chapt 1C; Dynamics of membrane lipids; Chapt 1D - Lipids in Water: Thermodynamics (to red line) (Review Thermodynamics );Quiz PC	Driving Force: THERMODYNAMICS - A REVIEW; Molecular Mechanics and Dynamics: SUPPLEMENT - MOLECULAR MECHANICS AND DYNAMICS Pre-class Question: 1C - Lipid Dynamics
4	1/21 W A2	Chapt 1D - Lip Water: Thermodynamics Chapt 1E - Why Micelles, Bilayers? Chapt 1F - What's New?	Lipids: Lipid Structure 1F: LIPIDS AS BIOLOGICAL SIGNALS Pre-Class Questions: Lipid Structure D. Lipids in Water - Thermodynamics - Question
5	1/23 F A4	Literature Learning Module: Lipids	This is a very difficult assignment. Don't panic. Do all of the questions, but your group will be assigned to present one of them in class.
6	1/27 T A6	Chapt 2A - Prot/A. Acids	PROBLEM SET 1: Lipids DUE Charges on Amino Acids and Proteins: Protein Structure 2A: THE STRUCTURE AND PROPERTY OF AMINO ACID; Buffers - Protein Structure 2A: THE STRUCTURE AND PROPERTY OF AMINO ACIDS Amino Acids: Protein Structure 2A: THE STRUCTURE AND PROPERTY OF AMINO ACIDS Pre-Class Questions: Protein Structure: Structure and Properties of Amino Acids - Question
7	1/29 R A2	Chapt 2B - Prot: Compo, Sequence, Conform. PS1 Due	Proteins 1 Protein Structure 2B: PROBING COMPOSITION, SEQUENCE, AND CONFORMATION
8	2/2 M A4	Chapt 2C - Prot: Conformation	Proteins 2: Protein Structure 2C: UNDERSTANDING PROTEIN CONFORMATION
9	2/4 W A6	Chapt 2D: Protein Folding/Stability	Protein Folding and Degradation: Protein Structure 2D: PROTEIN FOLDING/STABILITY IN VIVO AND IN VITRO
10	2/5 F B2	Chapt 2E: Lab Det ΔG^o; Chapt 2F: Thermo and IMF in Protein Fold/Stab. Read up to RED LINE	Pre-Class Questions: Determine the ΔG^o of unfolding from actual data Pre-Class Questions: Protein Structure: F. Thermodynamics and IMF - Electrostatics - Question
11	2/10 T B4	Chapt 2F: Thermo and IMF in Protein Fold/Stab. Finish	Pre-Class Questions: Protein Structure: F. Thermodynamics and IMF - H Bonds - Question Pre-Class Questions: Protein Structure: F. Thermodynamics and IMF - Hydrophobic Effect - Question
12	2/12 R B6	Chapt 2F: New Studies on Protein Stability (from GREEN LINE to end) Chapt 2G: Predict 2⁰ and 3^o struct; Chapt 2 H: Prot. Aggregates	read
13	2/16 M B2	Literature Learning Module: Proteins	PROBLEM SET 2A: Protein Analysis: Traditional Due Do it
14	2/18 W B4	Chapt 3A: Mono/Disacch. Chapt 3B: Complex Oligos	Mini Test 1: Lipids and Proteins Tue 2/17-Fri 2/20 Carbohydrates 1: Chapter 3A: MONOSACCHARIDES AND DISSACHARIDES Carbohydrates 2: Chapter 3B: COMPLEX OLIGOSACCAHRIDES
15	2/20 F B6	Chapt 3C: Glycoproteins Carbohydrate Jeopardy
16	2/24 T B2	Chapt 5A: Binding - Eq., Curves Chapt 5B: Rev. Binding I	Binding: Chapt 5B: REVERSIBLE BINDING 2
17	2/26 R B4	Chapt 5C: Mb, Hb and O2 to BC Optional	Myoglobin and Hemoglobin: Chapt 5C: A MODEL BINDING SYSTEM - MB, HB, AND DIOXYGEN PROBLEM SET 2B: Protein Analysis Using Web-based Proteomics Tools - optional 3/2/08 Pre-Class Questions: Binding: C. Hemoglobin and Myoglobin - Question
SPRING BREAK 2/27-3/6
18	3/9 M B6	Chapt 5C and 5D: binding and gene expression	Read
19	3/11 W C2	Chapt 5D: binding and gene expression; Chapt 5E: Drug Dev.	Transcription: Chapt 5D: BINDING AND THE CONTROL OF GENE TRANSCRIPTION Pre-Class Questions: Binding: D. Transcripton - Question
20	3/13 F C4	Literature Learning Module: Binding	PROBLEM SET 3: BINDING Due PROBLEM SET 4: THE CENTRAL DOGMA OF BIOLOGY Do it
21	3/17 T C6	Chapt 6A: Diffusion	Mini Test 2: CHO and Binding Wed 3/12-Fri 3/14 PROBLEM SET 4: THE CENTRAL DOGMA OF BIOLOGY Test 2: W-F Facilitated Diffusion: Chapt 6A: PASSIVE AND FACILITATED DIFFUSION
22	3/19 R C2	Chapt 6B: Rap. Eq/SS Enz. Kinetics	Enzyme Kinetics 1: Chapt 6B: Rapid Equilbrium and Steady State Kinetics Enzyme Kinetics 2: Chapt 6B: Rapid Equilbrium and Steady State Kinetics
23	3/23 M C4	Chapt 6C: Models of Inhib. Chapt 6D: More Complicated Models of Enz. Catalysis;
24	3/25 W C6	Literature Learning Module: Binding	Do it
25	3/27 F C2	Chapt 7A: Catalysis
26	3/31 T C4	Chapt 7B: Mech. Enz. Catalyzed Rxs	Enzyme Mechanisms: Chapt 7B: MECHANISMS OF ENZYME-CATALYZED REACTIONS
27	4/2 R C6	Chapt 7C: Cofactors and Electron Pushing	PROBLEM SET 5: ELECTRON PUSHING DUE
28	4/6 M D2	Chapt 7D: Enz. Cat. Rxs in Organic Solvent; Chapt 7E: Ribozymes
29	4/8 W D4	Literature Learning Module: Catalysis	Do it
EASTER RECESS: 4/9 - 4/13
30	4/15 W D6	Chapt 8A: Chem O₂ Chapt 8B: Biol. Oxidation Rxs	Mini Test 3: Diffusion, Enzyme Kinetics, Enzyme Mechanisms Mon 4/14-Wed 4/16
31	4/17 F D2	Chapt 8B: Biol. Oxidation Rxs	Pre-Class Questions:: Using Reduction Potentials:
32	4/21 T D4	Chapt 8C: ATP and OxPhos	Glycolysis: Chapt 8C: ATP AND OXIDATIVE PHOSPHORYLATION REACTIONS General Metabolism: Chapt 8C: ATP AND OXIDATIVE PHOSPHORYLATION REACTIONS
SCHOLARSHIP AND CREATIVITY DAY: 4/22
33	4/24 F D6	Chapt 8C: ATP/Oxphos; Chapt 8D: Photosynth. Chapt 9A: Nrg - ATP	Electron Transport: Chapt 8C: ATP AND OXIDATIVE PHOSPHORYLATION REACTIONS ATP Synthesis: Chapt 8C: ATP AND OXIDATIVE PHOSPHORYLATION REACTIONS Photosynthesis: Chapt 8D: PHOTOSYNTHESIS: THE LIGHT REACTION Pre-Class Questions: Signal Transduction: 9A. ATP - Question
34	4/28 T D2	Chapt 9B: Neurochem	Active Transport: Chapt 9A: ENERGY TRANSDUCTION: USES OF ATP Pre-Class Questions: Signal Transduction: 9B. Nerves - Question
35	4/30 R D4	Chapt 9C: Kinases, Phosphatases Web Survey	Signal Transduction: Chapt 9C: SIGNAL TRANSDUCTION AT CELL MEMBRANES
36	5/4 M D6	. Eric Kandel: Nobel Lecture, 2000 2009 class: Influenza and the 1918 Pandemic	Web Survey Instrument Number: 8457 Password: cookie name no caps no spaces (instructor) bu lao gou
Final Exam: MAY 6, WEDNESDAY,10:30 AM-12:30 PM - Computer Room - ASC 135 CSB

BIOCHEMISTRY - BCHM 321

COURSE SYLLABUS - SPRING 2009