Biochemistry Online:

An Approach Based on Chemical Logic

Dr. Henry Jakubowski
Last Update: 05/13/2008

 

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Table of Contents    

Preface

Chapter 1:  LIPID STRUCTURE
  1. Lipid Structure
  2. Lipids in Water : Structure
  3. Dynamics of Membrane Lipids
  1. Lipids in Water: Thermodynamics
  2. Why do Single Chain Amphiphiles form Micelles not Bilayers, and Double Chain Amphiphiles from Bilayers and not Micelles?
  3. Lipids as Biological Signals

Lipid Structure:  Literature Learning Module

Chapter 2:  PROTEIN STRUCTURE
  1. The Structure and Property of Amino Acids
  2. Composition, Sequence and Conformational Analyis of Proteins;
  3. Understanding Protein Conformation
  4. Proteins Folding - In Vivo and In Vitro
  5. Laboratory Determination of DGo for Protein Folding/Unfolding
  6. Thermodynamics and IMF's in Protein Stability
  7. Predicting Protein Properties Using Computational Biology and Bioinformatics - Proteomics  
  8. Protein Aggregates - Not Just  Junk

Protein Structure:  Literature Learning Module

Chapter 3:  CARBOHYDRATES
  1. Monosaccharides and Disssacharides
  2. Complex Oligosaccharides
  3. Jeopardy |  (scrambled list of all Jeopardy answers for which you supply the correct question)
  4. Glycoproteins:  Biosynthesis and Function
Chapter 4:  DNA, GENOMICS, AND PROTEOMICS
  1. The Structure of DNA
  2. The Central Dogma of Biology
  3. The Language of DNA
  4. Genomes and Other Omes (not Gnomes)
Chapter 5:  BINDING
  1. Reversible Binding I: Equations and Curves
  2. Reversible Binding II: Experimental Binding Curves, Kd, and Error Analysis
  3. A Model Binding System: Myoglobin. Hemoglobin, and Dioxygen
  4. Binding and the Control of Gene Transcription:  
  5. New Methods in Drug Development

Binding:   Literature Learning Module

Chapter 6:  TRANSPORT AND KINETICS
  1. Passive and Facilitated Diffusion
  2. Steady State and Rapid Equilibrium Kinetics
  3. Models of Enzyme Inhibition
  4. More Complicated Enzymes

Transport and Kinetics:   Literature Learning Module

Chapter 7:  CATALYSIS
REVIEW:  ORGANIC CHEMISTRY 
  1. Methods of catalysis
  2. Mechanisms of enzyme-catalyzed reactions
  3. Cofactors and Electron Pushing: Sources and Sinks
  4. Enzyme catalyzed reactions in organic solvents
  5. Ribozymes and the RNA World

Catalysis:  Literature Learning Module

Chapter 8:  OXIDATION/PHOSPHORYLATION
  1. The Chemistry of Dioxygen
  2. Biological Oxidation Reactions - Dehydrogenases, Mono and Dioxygenases, and Oxidases
  3. ATP and Oxidative Phosphorylation Reactions
  4. Photosynthesis: The Light Reaction

Oxidation/Phosphorylation:  Literature Learning Module

Chapter 9:  SIGNAL TRANSDUCTION
  1. Energy Transduction: Uses of ATP
  2. Signal Transduction: Neurochemistry
  3. Signal Transduction at Cell Membranes: Protein Kinases/Phosphatases
  4. Apoptosis - Programmed Cell Death  and Signal Transduction
  5. Memory and Learning in Apylsis 

New 12/16/06 Capstone: The Origin of Life

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©Copyright 2002 Dr. Henry Jakubowski
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